Tuesday 21 May 2013

Google Glass Year In Review

glassphotoIt’s been a little over a year since Google started teasing something it called “Project Glass.” The futuristic, wearable computer that would change the way that you interact with the world was nothing more than a series of rumors for months before it was “formally introduced” in April 2012. Not known for hardware and not having a current bonafide physical device that was popular among consumers, many opined that this was Google’s way of begging for attention. It might have been, and it definitely worked. In thirteen months, Glass has gone from Star Trek fantasy to reality. It’s been quite the whirlwind of activity. The “wearable computing” age is upon us, and it’s been widely reported that Apple was working on a watch, therefore many assumed that Google was working on a similar device to keep up. This was clearly not the case and Google’s co-founder Sergey Brin took special interest in the Glass project and has been leading the charge going back to when prototype weighed around eight pounds in August 2011. Let’s take a stroll down memory lane, as a lot has happened over the past year in Glassland. It’s real(ish) The video from Google itself got sent people’s imaginations into overdrive. It was called “One day…” and gave us a glimpse into the life of a daily user of what Google had up its sleeve. We now know that the “One day…” reference had more to do with what the product could become, not what it would be in its first iteration: The user experience in this video is aspirational, at best, as the current iteration of Glass is more of a compliment and utility to your day, rather than the augmented reality “enhancer” as this video demonstrates. Still, the elements that make Glass handy are all there, taking calls, getting directions and taking pictures from a new point of view. Immediately after the video, and public admonishment that the project was real, the press wondered out loud if Apple should compete and that other companies should stand up and take notice. We also now know that the rumored final name for the device, Google Eye, isn’t likely. Good thing, because it sounds way creepier than Glass. We’ll get to more “creepiness” later. It was clear that Glass was getting a lot of attention, both positive and negative, from the start. Even Jon Stewart did a parody

Source: http://feedproxy.google.com/~r/Techcrunch/~3/WHB8RZON7IE/

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Apple, Congress spar over taxes ahead of Tuesday hearing

By Patrick Temple-West and Poornima Gupta

WASHINGTON/SAN FRANCISCO (Reuters) - Using an unusual global tax structure, Apple Inc has kept billions of dollars in profits in Irish subsidiaries to pay little or no taxes to any government, a Senate report on the company's offshore tax structure said on Monday.

In a 40-page memorandum released a day before Apple CEO Tim Cook is scheduled to testify before Congress, the Senate's Permanent Subcommittee on Investigations identified three subsidiaries that have no "tax residency" in Ireland, where they are incorporated, or in the United States, where company executives manage those companies.

The main subsidiary, a holding company that includes Apple's retail stores throughout Europe, has not paid any corporate income tax in the last five years.

The subsidiary, which has a Cork, Ireland, mailing address, received $29.9 billion in dividends from lower-tiered offshore Apple affiliates from 2009 to 2012, comprising 30 percent of Apple's total worldwide net profits, the report said.

"Apple has exploited a difference between Irish and U.S. tax residency rules," the report said.

Apple said in a comment posted online on Monday it does not use "tax gimmicks." It said the existence of its subsidiary "Apple Operations International" in Ireland does not reduce Apple's U.S. tax liability and the company will pay more than $7 billion in U.S. taxes in fiscal 2013.

Subcommittee staffers said on Monday that Apple was not breaking any laws and had cooperated fully with the investigation.

CODE OVERHAUL SOUGHT

Tuesday's hearing is the second to be held by Senator Carl Levin, a Michigan Democrat and chairman of the subcommittee, to shed light on the weaknesses of the U.S. corporate tax code. Levin has sought to overhaul the code in Congress.

Lawmakers globally are closely scrutinizing the taxes paid by multinational companies. In Britain, Google faces regulatory inquiries over its own tax policies, while Hewlett-Packard Co and Microsoft Corp have been called to Capitol Hill to answer questions about their own practices.

Corporations must pay the top U.S. 35-percent corporate tax on foreign profits, but not until those profits are brought into the United States from abroad. This exception is known as corporate offshore income deferral.

In submitted testimony ahead of Tuesday's hearing, Apple said any tax reform should favor lower corporate income tax rates regardless of revenue, eliminate tax expenditures and implement a "reasonable tax on foreign earnings that allows free movement of capital back to the US."

"Apple recognizes these and other improvements in the U.S. corporate tax system may increase the company's taxes," it said.

Large U.S. companies boosted their offshore earnings by 15 percent last year to a record $1.9 trillion, avoiding hefty tax bills by keeping the profits abroad, according to research firm Audit Analytics.

TAX SCRUTINY

Apple also uses two conventional offshore tax practices typical of multinational companies' tax-avoidance strategies, the report said.

Multinational corporations value goods and services moving across international borders from one corporate unit to another. Known as "transfer pricing," these moves are frequently managed to reduce corporations' global tax costs.

Apple's tax structure highlights flaws in the U.S. corporate tax code so that Congress "can effectively close the loopholes used by many U.S. multinational companies," Arizona Senator John McCain, the subcommittee's top Republican, said in a statement on Monday.

Levin, who announced he will retire at the end of 2014, introduced legislation in February to close tax loopholes. At a news conference on Monday, Levin said his bill should pass independent of any broader tax reform push in Congress.

McCain, the top Republican on the subcommittee, told the joint news conference he would co-sponsor Levin's bill, the first Republican to support the bill. He called Apple's tax practices "egregious, and (a) really outrageous scheme."

Similar legislation has been introduced in the House of Representatives.

Government tax officials from the Internal Revenue Service and Treasury Department also are scheduled to testify before the subcommittee on Tuesday.

(Reporting by Patrick Temple-West in Washington and Poornima Gupta in San Francisco; Editing by Howard Goller, Bernard Orr)

Source: http://news.yahoo.com/apples-stateless-subsidiaries-lower-tax-bills-senate-report-211338532.html

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Former Wyoming legislator worked to legalized MMA, now getting in the cage

As a state legislator in Wyoming, Bryan Pedersen helped author the bill to legalize and regulate MMA in his home state. This weekend, he will test that bill by fighting at the Colosseum Fight Series, the first fights in Cheyenne since the bill passed.

Pedersen, who is 38 years old, has trained in MMA for the past four years. Like many fighters, he originally tried out the sport for fitness reasons only. But once MMA was allowed in his state, and Cheyenne was set to host fights, Pedersen couldn't help but say yes to an offer to fight on the CFS card.

"This is not something I normally do," he said to the Wyoming Star-Tribune. "But I really believe in the sport."

He served for six years in the Wyoming state legislature. Now a financial consultant, he plans on making this both his debut and retirement bout. The weigh-ins will take place at a familiar venue for Pedersen -- the steps of the Wyoming State Capitol Building.

Pedersen is taking the fight seriously, as he drives an hour and a half daily to Easton Training Center in Colorado, the training home of UFC veteran Eliot Marshall.

"I have a goal," he said. "Without a goal, you wouldn?t do it. It creates a sense of urgency and panic. Because every day I?m not training, my opponent is probably getting better. And I?m not."

He's the latest government official to set his sights on the cage, though Pedersen appears to be taking his fight more seriously than the two mayors in south Florida who are planning a bout. Perhaps MMA should become part of the legislative process.

Source: http://sports.yahoo.com/blogs/mma-cagewriter/former-wyoming-legislator-worked-legalized-mma-now-getting-210946127.html

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Type A Machines previews aluminum-framed Series 1 Pro 3D printer

Image

If you've navigated through the endless sea of 3D printers at this weekend's Maker Faire, you may well have caught a glimpse of the Series 1 Pro, the latest offering from San Francisco-based Type A Machines. The printer, which is still in the "engineering concept" phase," trades its predecessor's wood frame for a more solid aluminum version. The WiFi-compatible device has a build volume of around 18 liters, according to the company, and will be available in the third quarter of this year. That's the printer up top, pictured alongside Mark II, a little robot printed on the original Series One. Down below, you'll find a short press release.

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Source: http://www.engadget.com/2013/05/20/type-a-machines/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Monday 20 May 2013

UK tries out new model for gene testing in cancer patients

By Kate Kelland

LONDON (Reuters) - Britain launched a research programme on Monday that should eventually allow all cancer patients to have access to the kind of genetic analysis that led Hollywood star Angelina Jolie to decide to undergo a double mastectomy.

The project, involving the Institute of Cancer Research (ICR) in London, the U.S. gene sequencing firm Illumina, geneticists and cancer doctors, aims to find a way to allow more cancer genes be tested in more people.

Researchers announcing the 2.7 million pound (2 million pounds) project, funded by the Wellcome Trust medical charity, stressed this was not a response to reports last week of Jolie's decision to undergo surgery to reduce her breast cancer risk.

"What we're trying to do here is develop processes that will allow comprehensive and systematic use of genetic information in cancer medicine so that (more people) will be able to benefit from the types of information and situations we were hearing about last week (with the Jolie story)," said Nazneen Rahman, head of genetics at the ICR and a leader on the new project.

Mutations in some genes, known as cancer predisposition genes, greatly increase the risk that a person will get cancer.

Jolie tested positive for a high risk gene mutation that made her about five times more likely to develop breast cancer than women who do not carry this mutation, according to the U.S. National Cancer Institute.

There are nearly 100 other known cancer predisposition genes, but in Britain - where most healthcare is part of the taxpayer-funded National Health Service - testing for them is currently very restricted.

Yet recent advances in reading the genetic code, known as gene sequencing, mean that looking for gene mutations is now faster and cheaper than ever - paving the way for gene testing eventually to become routine for all cancer patients.

"It is very important to know if a mutation in a person's genetic blueprint has caused their cancer," Rahman told reporters at a briefing in London.

"It allows more personalised treatment, so for example such people are often at risk of getting another cancer and may choose to have more comprehensive surgery, or may need different medicines, or extra monitoring."

The programme, called Mainstreaming Cancer Genetics, will use a new Illumina test called TruSight that can analyse 97 cancer predisposition genes within a few weeks for a few hundred pounds, Rahman said.

The new model will be piloted initially in women with breast or ovarian cancer at London's Royal Marsden hospital, but the team hopes it will in future be used across the country and in many more types of cancer.

($1 = 0.6582 British pounds)

(Reporting by Kate Kelland; Editing by Raissa Kasolowsky)

Source: http://news.yahoo.com/uk-tries-model-gene-testing-cancer-patients-141830759.html

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CDC says 20 percent of U.S. children have mental health disorders (Washington Post)

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Leader of Toots and the Maytals injured at concert

RICHMOND, Va. (AP) ? Officials say the leader of the reggae band Toots and the Maytals was injured when a 19-year-old man threw a bottle and hit the singer during a concert in Richmond.

Police said Sunday the man has been charged with aggravated assault. Authorities have not identified him.

The Richmond Times-Dispatch reports that (http://bit.ly/17PhlkD ) Frederick "Toots" Hibbert was treated at a hospital for a cut to his head and released.

Hibbert was hit by a glass bottle thrown from the crowd Saturday night as the band was performing at the Dominion Riverrock outdoor sports and music festival. The band stopped playing after he was hit.

Festival organizers say Hibbert was in good spirits despite the traumatic event and regretted that the concert had to be stopped early.

Source: http://news.yahoo.com/leader-toots-maytals-injured-concert-165248763.html

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Animal lovers take pets to social media - Rappler.com

SOCIAL MEDIA PETS. The Fifth Annual BlogPaws Conference brings together social media-savvy pet owners. All photos from the 'BlogPaws' Facebook pageSOCIAL MEDIA PETS. The Fifth Annual BlogPaws Conference brings together social media-savvy pet owners. All photos from the 'BlogPaws' Facebook page

TYSONS CORNER, USA - When Dexter the cocker spaniel tore a ligament in his hind leg a few weeks ago, he didn't suffer in silence. Instead, his owner wrote a blog post.

"The vet told me my dog needed surgery, and I thought, 'You know, there's got to be something else'," said Carol Bryant, who writes a "canine-centric online magazine" called A Fidose of Reality.

Readers responded to her blog entry, and told Bryant that Dexter didn't have to go under the knife. He had options, like laser therapy and a leg brace he'll be wearing for the next six months.

Dexter is recovering, and travelled with Bryant from rural Pennsylvania to Washington suburb Tyson's Corner for the biggest US gathering ever of pet bloggers -- people who embrace social media to rave about pets.

The Fifth Annual BlogPaws Conference, with 500 participants and perhaps as many critters, offers an opportunity for pet lovers to network, swap ideas and maybe win a coveted Nose-to-Nose Pet Blogging and Social Media award (for which The Intrepid Pup, about a peripatetic Vizsla called Tavish, is nominated in three categories).

Workshops include a primer on using Google Analytics to gauge online readership and building bridges between bloggers and veterinarians. They also feature Schmitty the Weather Dog, who demonstrates a just-released Sony canine video harness.

BlogPaws has 2,200 members in its online community, said co-founder Yvonne DiVita, who writes about her cat and three dogs in Colorado on a blog titled Scratchings and Sniffings.

"I would guess we're going to hit close to 3,000 by the end of the year," she told AFP as the predominantly female bloggers and their pets--mostly dogs--took over the lobby of the Sheraton hotel on Thursday.

BLOG PAWS. An annual get together of pet bloggersBLOG PAWS. An annual get together of pet bloggers

The animal market

With Americans spending $53.33 billion on their pets last year, according to the American Pet Products Association, and 62 percent of households owning a pet, the pet care industry is taking the bloggers seriously.

In an exhibition hall, big hitters like pet food maker Nestle Purina rub shoulders with upstarts like the Spoiled Pup Boutique, a New York area canine couturier, all wooing bloggers to test and endorse their products.

"The followers and readers of pet blogs are so loyal, and they trust the word of bloggers," said Bridget Evans, a San Diego publicist attending BlogPaws for VetIQ, a newcomer to the pet medication and health supplements business.

It's come to the point, DiVita said, where some popular bloggers with solid track records and substantial followings can give up their day jobs and earn a good middle-class income -- or better -- through online advertising.

"I know bloggers that are making upwards of six figures," she said, while others are content with just a few hundred dollars.

The new online superstars

"We're kind of the rock stars of the pet industry," added Bryant, who cautions that the key to blogging success is finding a unique voice and then keeping it real.

"You need to be yourself when you blog."

Longtime syndicated pet columnist Steve Dale said his blog, which he updates daily, is one of the most popular among 200 blogs hosted by the Chicago Tribune's Chicago Now website, attracting 100,000 visitors a month.

"It's pretty incredible that a pet blog would be among the top 20 ... and here's my secret: I have no idea what I'm doing," Dale, the owner of two mutts, a cat and a northern blue-tongued skink lizard, told AFP.

Actually, he does have an idea: blogging enables Dale to cover breaking news--"In the pet world, there is news, believe it or not"--like a pet food recall that otherwise wouldn't make his twice-weekly print column My Pet World.

"It can be anything, and bingo! Bongo! I can cover it," he said.

Dale was a keynote speaker at BlogPaws, and is keen to draw fellow bloggers' attention to some worrying pet health trends. There are fewer pets getting check-ups at the vets, for instance, and upticks in flea infestations and heartworm.

Julia Gleason from San Francisco hopes her year-old fashion-meets-Fido blog Canines and Couture, which often features her English bulldog, will grow to a stage where she bid farewell to her day job at a legal consultancy.

"I have lofty goals to turn it into an actual business at some point," she told AFP as Chilly, a white poodle with a dyed purple head and tail, chilled out on the floor by the wine bar.

"Right now, I'm focusing on building my audience and building a following."

CHILLY. A purple headed poodle chills out at the BlogPaws conferenceCHILLY. A purple headed poodle chills out at the BlogPaws conference- Rappler.com

Source: http://www.rappler.com/life-and-style/29554-animal-lovers-take-pets-to-social-media

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Consuming coffee linked to lower risk of an autoimmune liver disease

May 18, 2013 ? Regular consumption of coffee is associated with a reduced risk of primary sclerosing cholangitis (PSC), an autoimmune liver disease, Mayo Clinic research shows. The findings were being presented at the Digestive Disease Week 2013 conference in Orlando, Fla.

PSC is an inflammatory disease of the bile ducts that results in inflammation and subsequent fibrosis that can lead to cirrhosis of the liver, liver failure and biliary cancer.

"While rare, PSC has extremely detrimental effects," says study author Craig Lammert, M.D., a Mayo Clinic gastroenterologist. "We're always looking for ways to mitigate risk, and our first-time finding points to a novel environmental factor that also might help us to determine the cause of this and other devastating autoimmune diseases."

The study examined a large group of U.S. patients with PSC and primary biliary cirrhosis (PBC) and a group of healthy patients. Data showed that coffee consumption was associated with reduced risk of PSC, but not PBC. PSC patients were much likelier not to consume coffee than healthy patients were. The PSC patients also spent nearly 20 percent less of their time regularly drinking coffee than the control.

The study suggests PSC and PBC differ more than originally thought, Konstantinos Lazaridis, M.D., a Mayo Clinic hepatologist and senior study author says: "Moving forward, we can look at what this finding might tell us about the causes of these diseases and how to better treat them."

The National Institutes of Health funded part of this with a grant to principal investigator Dr. Lazaridis. The American Liver Foundation awarded Dr. Lammert a postdoctoral research fellowship.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/EkC5grtUHqw/130518153254.htm

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Sunday 19 May 2013

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HTC says One production will double to meet ?strong demand?

WASHINGTON -- The one thing no one has suspected Dzhokhar Tsarnaev of being is a closet essayist. The idea of this young Chechen/Dagestani/Khrgyz man who, with his brother is accused of the vicious Boston Marathon bombings, making notes on his ideas had not entered the bio.And yet, as I write, news sources are reporting new information about Dzhokhar. Lying helplessly in the landlocked boat he was hiding inside of, in the small Massachusetts town outside Boston where they had fled, he wrote several primitive but revealing thoughts on the hull of the bullet-pocked boat with a pen he found. ...

Source: http://news.yahoo.com/htc-says-one-production-double-meet-strong-demand-230024068.html

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2 fires north of LA persist after long fire week

AAA??May. 18, 2013?5:33 PM ET
2 fires north of LA persist after long fire week
AP

Mike Whitaker, left, and Andrew Fullingim watch smoke from a brush fire from Lake Hughes in Castaic, Calif., Friday, May 17, 2013. (AP Photo/Santa Clarita Valley Signal, Jonathan Pobre) MANDATORY CREDIT, LOS ANGELES DAILY NEWS OUT

Mike Whitaker, left, and Andrew Fullingim watch smoke from a brush fire from Lake Hughes in Castaic, Calif., Friday, May 17, 2013. (AP Photo/Santa Clarita Valley Signal, Jonathan Pobre) MANDATORY CREDIT, LOS ANGELES DAILY NEWS OUT

The Grand fire releases a large plume of smoke as it burns more than 3,000 acres of wildlands near Frazier Park on Wednesday, May 15, 2013.Cooler temperatures and lighter winds are helping hundreds of firefighters combat a 3,000-acre wildfire. (AP Photo/Los Angeles Times, Luis Sinco) OUTS; ORANGE COUNTY REGISTER, LA DAILY NEWS, VENTURA COUNTY STAR, INLAND VALLEY DAILY BULLETIN, LA OPINION), SOMETIMES: -CALON (LONG BEACH PRESS-TELEGRAM) NO FORNS, NO SALES, MAGS OUT, MANDATORY CREDIT

A firefightier watches a backfire set in Hungry Valley State Park to halt the prgress of the Grand fire, which charred more than 3,000 acres of wildlands near Frazier Park on Wednesday, May 15, 2013. Cooler temperatures and lighter winds are helping hundreds of firefighters combat a 3,000-acre wildfire. (AP Photo/Los Angeles Times, Luis Sinco) OUTS; ORANGE COUNTY REGISTER, LA DAILY NEWS, VENTURA COUNTY STAR, INLAND VALLEY DAILY BULLETIN, LA OPINION), SOMETIMES: -CALON (LONG BEACH PRESS-TELEGRAM) NO FORNS, NO SALES, MAGS OUT, MANDATORY CREDIT

The Grand fire burns into the Los Padres National Forest near Gorman, Calif., where the blaze charred more than 3,000 acres of wild lands on Wednesday, May 15, 2013. Wednesday, May 15, 2013. Cooler temperatures and lighter winds are helping hundreds of firefighters combat a 3,000-acre wildfire. (AP Photo/Los Angeles Times, Luis Sinco) OUTS; ORANGE COUNTY REGISTER, LA DAILY NEWS, VENTURA COUNTY STAR, INLAND VALLEY DAILY BULLETIN, LA OPINION), SOMETIMES: -CALON (LONG BEACH PRESS-TELEGRAM) NO FORNS, NO SALES, MAGS OUT, MANDATORY CREDIT

Smoke billows over a neighborhood in Castaic, Calif., as parents line up in their cars along to pick up students from a nearby elementary school, Friday, May 17, 2013. As firefighters took on a stubborn 3-day-old wildfire Friday in rough terrain north of Los Angeles, a second and more serious blaze broke out 30 miles away near Interstate 5, quickly surging to more than 500 acres, briefly threatening an elementary school and leading to the precautionary evacuation of nearly 20 homes. (AP Photo/Santa Clarita Valley Signal, Jonathan Pobre) MANDATORY CREDIT, LOS ANGELES DAILY NEWS OUT

(AP) ? A pair of persistent wildfires continued to burn in the hills and mountains around Interstate 5 north of Los Angeles on Saturday, although authorities were slowly getting the upper hand.

A new fire that broke out Friday, the third major blaze in the area in a week, quickly surged to 712 acres Friday and briefly threatened an elementary school and about 20 homes. Some 350 firefighters, who battled both flames and unpredictable winds, were able to hold the line against it Saturday morning, however. It was 75 percent contained.

Crews were helped by relatively mild temperatures that were expected to remain into the weekend, but challenged by the unpredictable winds and very difficult terrain.

With air and ground attacks, firefighters were able to douse the flames closest to Northlake Hills Elementary School and stop a looming threat.

The school had a large defensible space around it, so it was easy to protect, Los Angeles County Fire Inspector Scott Miller said.

The campus was put on lockdown and buses were put on standby for a time in case hundreds of kindergarten through fifth-grade students needed to be evacuated.

After the flames were redirected, Los Angeles County Sheriff's Sgt. Brian Allen said the students were released to their parents without incident.

The fire was moving toward Castaic Lake.

The earlier fire that broke out Wednesday near Frazier Park was 70 percent contained Saturday after consuming some 4,358 acres.

That blaze was not threatening any homes or buildings but fire officials said containing it would be a long, difficult task because it was burning in such rugged and hard-to-reach terrain.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-05-18-California%20Wildfire/id-74f68a3b21cb445faad2a41d5880e66e

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X-ray tomography on a living frog embryo

Friday, May 17, 2013

Classical X-ray radiographs provide information about internal, absorptive structures of organisms such as bones. Alternatively, X-rays can also image soft tissues throughout early embryonic development of vertebrates. Related to this, a new X-ray method was presented recently in a Nature article published by a German-American-Russian research team led by KIT. For periods of about two hours, time-lapse sequences of cellular resolution were obtained of three dimensional reconstructions showing developing embryos of the African clawed frog (Xenopus laevis). Instead of the absorption of X-rays, the method is based on their diffraction (DOI: 10.1038/nature12116).

"X-ray diffraction enables high-resolution imaging of soft tissues," explains Ralf Hofmann, one author of the study and physicist at KIT. "In our work, we did not only manage to resolve individual cells and parts of their structure, but we could also analyze single cell migration as well as the movement of cellular networks."

Using X-ray diffraction, similar tissues can be distinguished by minute variations of their refractive index. However, in contrast to classical absorption imaging, this does not require any contrast agent, and X-ray dose is profoundly reduced. The method is of particular advantage when probing sensitive tissues in living organisms, such as frog embryos. In their study, the researchers concentrated on the motion and shape changes of tissues, cavities, and single cells during the developmental milestone of gastrulation.

During gastrulation, germ layers are formed and organized in their proper locations. Thereby, an initially simple spherical ball of a few hundred cells turns into a complex, multilayered organism with differentiated tissues eventually turning into the nervous system, muscles, and internal organs. Quoting the renowned developmental biologist Lewis Wolpert: "it is not birth, marriage, or death, but gastrulation that is the most important event in your life."

"Employing X-rays, we were able to watch joint and individual cell movements during gastrulation," zoologist Jubin Kashef points out who is a co-author and head of a young investigator group at KIT. For the first time, it was appreciated how cells interact with each other in a living embryo and how regions void of cells form and disappear. "It is like the migration of peoples. Stimulated by the migration of individual cell groups, other cells join in. They form functional cellular networks, which adjust to their changing environment. During migration, cells specialize to form progenitor tissues of future organs, e.g. the brain or skin."

"It is fascinating to have digital capabilities to observe and analyze these processes in an individual living frog embryo," Hofmann and Kashef emphasize. "In this way, fundamental results are obtained." The new method not only reveals morphological and dynamic aspects of embryonic development but also provides insights into their underlying molecular biology obtained by comparing the development of wildtype embryos and morphant phenotypes. The African clawed frog (Xenopus laevis) is one of the most important model systems of developmental biology whose study is of relevance in understanding human embryogenesis and diseases. In future research, morphant phenotypes will be correlated with the targeted switch-offs of key proteins. For this purpose, the novel technique -- combining latest X-ray measurement technology with advanced image analysis and developmental biology -- will be established at the synchrotron radiation facilities ANKA in Karlsruhe and APS in Chicago for routine use by a broad community of scientific users.

In their study, KIT researchers, which were supported by biologists from Northwestern University, used coherent X-rays from the Advanced Photon Source of Argonne National Laboratory in Chicago. Prior to this investigation, the method had been developed at ANKA. During measurement, a coherent bundle of X-rays passes the nearly spherical 1-mm frog embryo, which rotates half way around its axis within 18 seconds. By variation of the irradiation direction, information on the three-dimensional (3D) structure is acquired. As X-rays pass through different types of tissues at variable speeds, diffraction occurs. In turn, this generates a characteristic intensity distribution by interference a certain distance behind the embryo. Within the 18 s of tomographic scan time, about 1200 images were recorded. Similar to digital photography, every image consists of several million pixels. From this vast amount of data, the three-dimensional structure and the development of the embryo over time is inferred at micrometer resolution. If this process is repeated at intervals of several minutes, the resulting sequence of 3D images reveals all gastrulation movements occurring inside the embryo. Image reconstruction and analysis algorithms for the here-employed X-ray phase-contrast microtomography were developed at ANKA.

Immediate results of this research are the discovery of new morphological structures and the clarification of fluid redistribution processes. Moreover, the locations of centers driving the migration of tissues and cells during gastrulation were determined by differential flow analysis.

###

Helmholtz Association of German Research Centres: http://www.helmholtz.de/en/index.html

Thanks to Helmholtz Association of German Research Centres for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 62 time(s).

Source: http://www.labspaces.net/128293/X_ray_tomography_on_a_living_frog_embryo

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Former soap actor arrested for selling cocaine

Celebs

4 hours ago

Dylan Patton in 2010.

Getty Images file

Dylan Patton in 2010.

Dylan Michael Patton, who earned a Daytime Emmy nomination for his role on NBC soap "Days of Our Lives," was charged on Thursday with selling cocaine from his home, according to the Los Angeles Times.

The 20-year-old actor played Will Horton for just under a year on the long-running soap and also appeared in such TV series as "Cold Case" and "That's So Raven." He was arrested Tuesday after sheriff's deputies searched his family's home in Agoura Hills, near Los Angeles.

Horton now faces one count of possession for sale of a controlled substance and was slated to be arraigned on Thursday. The Times said he was expected to plead not guilty, and that he allegedly sold the cocaine within 1,000 feet of an elementary school.

California law's health and safety codespecifies that if heroin, cocaine or a cocaine-based substance are sold near a school (or place of worship or facilities with minors present) the penalties for the sale can be increased in severity.

Patton could face up to nine years in state prison if he is convicted, and prosecutors were expected to ask the judge to set bail at $30,000.

Source: http://www.today.com/entertainment/ex-days-our-lives-actor-charged-selling-cocaine-out-home-1C9965351

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Saturday 18 May 2013

Crosby leads Penguins to 4-3 win over Senators

PITTSBURGH (AP) ? Sidney Crosby had his second career playoff hat trick and the Pittsburgh Penguins beat the Ottawa Senators 4-3 on Friday night to take a 2-0 lead in the Eastern Conference semifinals.

Brenden Morrow added his first playoff goal in more than five years, Tomas Vokoun made 19 saves and the Penguins rode their superstar captain to their fourth straight victory.

Crosby beat Craig Anderson three times in the game's first 22 minutes, sending the goalie to the bench after stopping 18 of 21 shots.

Kyle Turris, Colin Greening and Jean-Gabriel Pageau scored for the Senators, but couldn't stop Ottawa from falling into a deep hole against the Eastern Conference's top seed. The Senators have never won a playoff series after dropping the first two games.

Game 3 is Sunday in Ottawa.

The Senators insisted they didn't have to play a perfect game to hang with the Penguins, pointing to the way they controlled play at even strength for long stretches in a 4-1 loss in the series opener Tuesday night. Ottawa insisted if it could stay out of the penalty box and convert when it had the man advantage, it would be right there.

Despite doing both in the first period ? killing two penalties and converting on Turris' bank shot on the power play ? the Senators still trailed 2-1.

More to the point, they trailed Crosby 2-1.

The Pittsburgh captain became the fifth player in franchise history to record 100 playoff points in spectacular fashion. He collected an innocent-looking pass at the Pittsburgh blue line then darted up the left side. He split two Senators ? including Norris Trophy-winning defenseman Erik Karlsson ? then ripped a shot under Anderson's pad to give the Penguins the lead 3:16 into the game.

Turris tied it with the first soft goal Vokoun has allowed since taking over for Marc-Andre Fleury in Game 5 of the first-round series against the Islanders. Turris collected the puck near the left post and shot it off Vokoun and into the net.

Crosby one-upped Turris a few minutes later, zipping down the left side once again. This time, Crosby appeared to be looking to pass, eyeing linemate Pascal Dupuis as they raced in on Anderson. Only Crosby didn't pass. At the last second and without even peeking directly at Anderson, he flipped a wrist shot near the goal line that smacked off the goalie's pad and into the net.

Karlsson, who is still working his way back from an Achilles injury sustained when Pittsburgh's Matt Cooke inadvertently slashed Karlsson with his skate, drew a hooking penalty on Cooke early in the second.

Crosby didn't need any fancy stickwork to record his first postseason hat trick since 2009. Instead he powered a slap shot over Anderson's glove from the left circle to push Pittsburgh's lead to 3-1. Anderson skated to the bench in favor of backup Robin Lehner.

Greening responded almost immediately after the switch, beating Vokoun with a sizzling wrist shot 40 seconds later to get the Senators within one. Morrow restored the two-goal lead by redirecting Paul Martin's blast from just outside the crease. It was Morrow's first postseason score since May 14, 2008, while playing for the Dallas Stars.

The score was one of the few mistakes made by Lehner in his playoff debut. The 21-year-old was stellar otherwise in relief of Anderson. He made 20 saves in all, including series of point-blank stops. He robbed Jarome Iginla on a 2-on-1 shortly after entering and used perfectly a timed slide to stone Evgeni Malkin on the doorstep in the third period.

Lehner's play steadied the Senators, and Ottawa kept coming, pulling within a goal 2:01 into the third period when Pageau tapped the puck across the line following a mad scramble in front.

The Senators, however, couldn't tie it as Pittsburgh remained unbeaten since Vokoun replaced Fleury and moved within two wins of making it to the conference finals for the first time since 2009 when the Penguins went on to win the Stanley Cup.

NOTES: Crosby reached the 100-point plateau in his 75th playoff game, the fifth-fastest player to reach the mark in NHL history ... Pittsburgh went 1 for 6 on the power play and is 10 of 30 (33 percent) in the postseason. The Senators went 1 for 2 after going 0 for 6 in the opener ... Ottawa D Eric Gryba didn't play. He was injured in a collision with Penguins D Brooks Orpik in the second period of Game 1

Source: http://news.yahoo.com/crosby-leads-penguins-4-3-win-over-senators-022133636.html

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Gunmen seize elderly father of Syria's deputy FM

DAMASCUS, Syria (AP) ? The office of Syria's deputy foreign minister says gunmen have abducted his elderly father in the southern Daraa province.

The office says Deputy Foreign Minister Faisal Mekdad's father was seized Saturday in the village of Ghossom in Daraa province.

An official in Mekdad's office said the elder Mekdad is over 80 years old, but did not immediately know his name.

There was no immediate claim of responsibility.

Source: http://news.yahoo.com/gunmen-seize-elderly-father-syrias-deputy-fm-132111295.html

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Google Glass rooted and hacked to run Ubuntu live at Google I/O

Google Glass rooted and hacked to run Ubuntu live at Google IO

Today at Google I/O the company held a session entitled "Voiding your Warranty" where employees demonstrated how to root Google Glass and install Ubuntu on it. What you're seeing above is a screenshot from a laptop running a terminal window on top and showing the screencast output from Glass on the bottom -- here running the standard Android launcher instead of the familiar cards interface. The steps involve pushing some APKs (Launcher, Settings and Notepad) to the device using adb, then pairing Glass with a Bluetooth keyboard and trackpad. After this, it's possible to unlock the bootloader with fastboot and flash a new boot image to gain root access. From there you have full access to Glass -- just like that! Running Ubuntu requires a couple more apps to be installed, namely Android Terminal Emulator and Complete Linux Installer. The latter lets you download and boot your favorite linux distro (Ubuntu, in this case). You're then able to use SSH or VNC to access Ubuntu running right on Glass. We captured a few screenshots of the process in our gallery. Follow the links below for more info -- just be careful not to brick your Glass okay?

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Source: Google I/O 2013

Source: http://www.engadget.com/2013/05/16/google-glass-rooted-and-hacked-to-run-ubuntu-live-at-google-i-o/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Noah Baumbach on ?Frances Ha': Why it took 40 takes to make a little story feel epic

By Steve Pond

LOS ANGELES (TheWrap.com) - Noah Baumbach's "Frances Ha" seemingly came out of nowhere to charm viewers at Telluride and Toronto last fall.

The Brooklyn-born director, whose previous films include "Kicking and Screaming," "The Squid and the Whale" and "Margot at the Wedding," made the made the movie quietly, co-writing it with his "Greenberg" leading lady Greta Gerwig and filming it in luminous black and white on the streets and in the subways and apartments of New York City.

The film follows Gerwig's title character, a 27-year-old aspiring dancer who's never quite gotten her life together; by turns funny, sad, touching and cringe-inducing, it approaches the mess that Frances has made with what TheWrap's Alonso Duralde described as "an optimism and empathy ? that feels genuine and earned."

TheWrap spoke to Baumbach about the Woody Allen connection, shooting up to 40 takes for each scene and the leap of faith needed on the part of financiers.

Warning: His final answer contains spoilers.

You approached Greta Gerwig about making another film together after finishing "Greenberg," but at that point how much of an idea did you have for this film?

I really just had a sense of a movie - doing something in New York that Greta would be the center of and maybe centering on being that age. I didn't really know much beyond that. But working with her on "Greenberg," I was struck by how hilarious she is, so I also had the sense that it could be funny.

So we just started emailing each other back and forth with pretty broad thoughts. They were things like, "Do you pay the surcharge at an ATM if you're in a rush and you're broke, instead of walking to a cheaper ATM?" Things like that that did make it into the movie, and then many things that didn't make it into the movie.

Did you decide to shoot in black and white early on?

That was one of my first ideas. I felt like the black and white would both contrast and support what was essentially a very modern story and a very contemporary character.

And also, there was something about the character as she developed where all my visual ideas started going toward a more classical mode of shooting. I wanted it to feel kind of elegant and beautiful and epic at times, and the black and white certainly was part of that, and later the music. There was something about the intimacy of the story that I felt should be told in a bigger, bolder way.

When you make the decision to make a movie in black and white in New York City, do you always feel the shadow of Woody Allen and his "Manhattan" cinematographer Gordon Willis? Well, of course we went right to that movie, to "Manhattan." And "Broadway Danny Rose." I felt like what we were doing was maybe in the tradition of it, but it was so much our story. It wasn't so much of a shadow so much as it was something to get inspiration from, as a kind of bar you want to try to hit.

You famously shot 30, 40 takes or more of many of the scenes in this film. What do you get out of a scene when you do it that many times?

Well, I'm often interested in how much story you can tell with one shot. And so sometimes I tend to shoot many pages in one shot, without a cutting point. If the scene were shot in a more traditional way, you'd ultimately be doing almost as many takes, because you'd be shooting a master and then medium close, then close ... So in some ways you'd be close to 40 takes anyway.

What we're trying to do, often, is to get many pages to work in one shot. Maybe that's where perfectionism comes into play. It's sometimes getting the camera move right or changing our minds in the middle and deciding to block it differently. Sometimes two actors are on different trajectories within a scene, and you need to get them both at the same place at the same time.

And sometimes it's me, and I'm having trouble figuring it out.

If you're shooting traditionally, using coverage, you can piece a scene together using the best lines from many different takes. But if you're shooting the whole thing in one shot, you have to hope that one take has everything you want. Exactly. My friend Brian DePalma says he thinks coverage is a bad word. He says anybody can shoot a scene with coverage. I do think it's more interesting to see how shots can evolve.

And it doesn't need to be with wild camera moves or anything. It can just be with blocking, having an actor start in the background and walk to the foreground as the scene develops. I was thinking in some cases of the way Woody Allen blocks scenes, or how Ernest Lubitsch would block a scene.

A black-and-white movie with a script that was kept under wraps - this must have been a leap of faith on the part of the financiers.

It was a major leap of faith. I told them I was going to be black and white, but I did tell them that it wasn't going to be experimental. I said it would be a movie that would stand with anything else I'd made. And they were really cool about it.

Not to give anything away, but there's something quite refreshing about an ending that feels like a small triumph, even though it's very much not what this character has spent the entire movie working toward and dreaming about.

Right. It was clear to me early on that the ending should be hopeful, that she should be rewarded for her struggles. At a Q&A recently, somebody said, "Did you ever think of not giving it such a happy ending?" And I think it was Greta who said the same thing you were just pointing out. She said, "It is a happy ending - but if you really kind look at it, she takes a desk job and gets a crummy little apartment. It's hardly like she's marrying a prince."

We really wanted to create a context where those moves seemed big. Heroic, in a way. It was a movie where acknowledging that you're not going to get what you fantasized about can be a very positive thing. That's what growth is, you know?

Source: http://news.yahoo.com/noah-baumbach-frances-why-took-40-takes-little-222224818.html

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9,000-acre wildfire in NW Wisconsin contained

TOWN OF GORDON, Wis. (AP) ? Firefighters battling a 9,000-acre in northwestern Wisconsin have contained the massive blaze.

Department of Natural Resources spokesman Robert Manwell said Thursday the fire in Douglas and Bayfield counties is 100 percent contained. Manwell says fire crews will be handling small brush fires and reworking the lines that contain the wildfire.

Authorities opened all roads in the area overnight and some residents headed back to their homes. The fire, which began Tuesday, destroyed 17 homes and 30 other structures. The DNR says no one has been hurt in the largest forest fire to hit northern Wisconsin in 33 years.

Gov. Scott Walker has declared a state of emergency in Douglas and Bayfield counties, which makes the Wisconsin National Guard available for recovery efforts. The governor plans to tour the area Thursday.

Source: http://news.yahoo.com/9-000-acre-wildfire-nw-wisconsin-contained-123821625.html

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Soccer-Oceania club final showcases future of broadcasting

By Greg Stutchbury

WELLINGTON, May 17 (Reuters) - The possible future of sports broadcasting will be further highlighted on Sunday when New Zealand's Auckland City and Waitakere United play the Oceania Champions League final, with the winner qualifying for the lucrative FIFA Club World Cup.

The match in Auckland, reduced to a winner-takes-all final after the Oceania Football Confederation (OFC) streamlined the competition this year, will be broadcast not only on television but also live over the Internet on the OFC's YouTube channel.

"The coverage will be screened live in New Zealand ...while those living in other parts of the world will be able to watch live streaming of the match free of charge on the OFC Live YouTube channel," the OFC said in a statement on Friday.

Pacific Islands broadcasters would also carry the OFC feed on television, though New Zealand-based fans would be unable to access the YouTube feed.

Struggling to gain a foothold in the television market in rugby-mad New Zealand, OFC TV, a FIFA-backed project, came to public prominence about a year ago when the OFC were unable to reach agreement with a New Zealand-based broadcaster to cover the Oceania Nations Cup in the Solomon Islands.

Pacific Island broadcasters did show the tournament, while New Zealand fans were offered the opportunity to watch pay-per-view games on the OFC website.

The OFC broadcast two of this year's Champions League semi-finals over the Internet as they tested their technology and quality of feed.

OFC TV head Olivier Huc was unavailable for comment on Friday, though he told the New Zealand Herald newspaper earlier this month that the Champions League coverage was a precursor to the full launch of the OFC YouTube channel in July.

Despite the novel way of broadcasting the match, both teams have focussed on clinching the title which carries a lucrative $500,000 payday and qualification for the FIFA Club World Cup in Morocco in December.

It is the first time that teams from the same country have contested the final.

Ramon Tribulietx's Auckland City will be seeking an Oceania record third successive trip to the FIFA tournament, which involves club champions from all six confederations.

The amateur side shocked world soccer when they made the quarter-finals of the tournament in 2009 and were competitive in their only match last year in Japan.

"Records and milestones are not really part of any talks we have within the squad - our focus is firmly on what we have to do as a team to get the right result," Tribulietx told the OFC website (www.oceaniafootball.com).

"We are convinced that we can win and will prepare to do the things we consider to be important in this game." (Editing by Patrick Johnston)

Source: http://news.yahoo.com/soccer-oceania-club-final-showcases-future-broadcasting-062953156.html

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Friday 17 May 2013

Google+ Hangouts app hands-on - Engadget

Google Hangouts app handson

Google's new, unified Hangouts platform focuses heavily on its mobile apps, which give Android and iOS users a common platform for text and video chats. In theory, they're the cure for the consistency problems Google's messaging systems have faced for years. But are they the fixes we've all been waiting for, the all-encompassing solutions that have us dropping the likes of Facebook Messenger or WhatsApp? We gave Hangouts a test on both Android and iOS to find out -- check our impressions after the break.

Google+ Hangouts app hands-on

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13 Photos

Getting set up with either Hangouts app is certainly easy. It just requires a quick sign-in on iOS, and it's virtually automatic on Android if you've used Google Talk (which Hangouts replaces) in the past. Most settings, such as notification options, are also in familiar places on Android. Notification snoozing is new: you can now tell the app not to bug you for a set period, such as when you're at work or the bar. Google's approach to managing its newly persistent chat history is potentially confusing, though. Rather than implement a global control, Google manages policy changes on a chat-by-chat basis. If you don't want to ever have a permanent (if private) record of what you've said, you'll have to make that choice every time. Google tells us that chats will disappear after 24 hours when the history is turned off.

It's when you get down to business that the changes are truly conspicuous. Google said it was structuring Hangouts around conversations, and it wasn't kidding: the view on starting the mobile app usually involves active and recent text and video sessions, rather than a list of chat candidates. Contacts are there, but you'll have to start a new Hangout or invite new participants to see them. It's more of a calculated trade-off than a uniformly positive improvement, in our view. While a conversations-first approach is handy for resuming any earlier activity, it's a bit counter-intuitive when you just want to see if a friend is available.

Google Hangouts app handson

We had no problems starting chats, however, and it's clear that Google spent a lot of time livening up the slightly boring Google Talk interface. It now behaves more like other recent messaging apps, with appealing uses of chat bubbles and emoji. Photos are new, and (mostly) work seamlessly -- hitting the relevant button brings up your device's default photo picker, and any image dropped into the chat should remain visible when switching devices. We do wish that audio and video were options.

Group video Hangouts are billed as new, although our experience showed that to be something of a misnomer. The minimalist interface will be familiar to those who've used Google's previous video-capable mobile apps. One nice touch in the new release is the slick integration with related chats. It's easy to tell if someone just posted a photo while you're in a video Hangout, and it's simple to rejoin that same session when it's in progress. Don't try to connect to a chat directly through AT&T (and possibly other carriers), though: at first blush, it appears that AT&T may be blocking Hangouts over its cellular network.

Cross-platform, the interaction and persistence were largely as good as we'd hoped. While we couldn't try Gmail integration on the desktop (we weren't getting the option), our Android and iOS testers could freely participate in conversations without feeling hamstrung, and completed Hangouts would reliably appear on other devices or the web. As many of us have multi-device households, we also have an extra level of appreciation for the smarter attitude towards notifications. Clear one alert on a device and you won't always have to deal with it on everything else you own, where OS features allow -- you'll still see an iOS notice on Android (or vice versa), but multiple Android devices and the web handle notifications elegantly. The Google+ web redesign (which could be a hands-on by itself) makes it a lot easier both to review mobile discussions and to see their related photos in one central location. Each session's photos are saved to a private album.

Google Hangouts app handson

Our early takeaway? If you're a Google+ fan, use at least one of Google messaging services or just want to give Google's services a shot, the Hangouts apps are welcome additions. They're simple to use, keep conversations going across platforms and consolidate multiple once-disparate services into one framework. The question is harder to answer for anyone wedded to another cross-platform messaging system. Facebook Messenger and WhatsApp already take on text chat and photo sharing while occasionally doing more, such as audio clips or locations. Google also hasn't dethroned Skype for live video, and can't do voice alone in the current Hangouts version. These rivals have some momentum on their side, too; it's hard to ignore a billion-plus Facebook users, while Google+ is comparatively young. The appeal for the unconverted may come mostly from Google's sheer reach. When Hangouts offers both text and video chat, and serves them equally through mobile apps and the web, it may be the one service that's always on hand.

Source: http://www.engadget.com/2013/05/15/google-hangouts-app-hands-on/

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